Georgia Institute of Technology College of Sciences

Research in the Barry laboratory combines molecular biophysics, spectroscopy, biochemistry, and chemical biology to study enzyme based catalysis. The role of metal ions in proton coupled electron transfer (PCET) reactions are of particular interest and are fundamental to solar energy conversion and DNA synthesis. New projects seek to synthesize biomimetic maquettes that can conduct PCET reactions, to define the role of intrinsically disordered peptides in the immune system, and to describe DNA-cisplatin interactions in vivo and in vitro.